Oxford Endovascular raises $10M to develop ‘origami’ medical system

by akoloy

Origami is extra historically related to the artwork of paper folding, however one British startup is utilizing the approach to develop a remedy for mind aneurysms.

Oxford Endovascular Ltd has raised $10 million in Series A funding for its OxiFlow resolution, which goals to beat challenges with present medical gadgets.

Vulpes Investment Management led the spherical, with the Additio Investment Group, Oxford Sciences Innovation PLC, Parkwalk Advisors, Perivoli Innovations, Oxford Investment Consultants, the University of Oxford and personal people following on.

The Oxford University spin-out has beforehand gained funding from the European Union’s Horizon 2020 SME instrument and the UK’s grant programme, Innovate UK.


Brain aneurysms have an effect on one in 50 folks and if a affected person suffers a rupture, there’s a excessive probability of loss of life or everlasting mind harm.

Oxford Endovascular’s OxiFlow micro stent was developed utilizing ‘origami engineering’, enabling its construction to be lowered and subsequently enlarged.

OxiFlow might be inserted into the mind blood vessels by way of minimally invasive groin entry. It lies throughout the bottom of the aneurysm and causes it to shrink and heal. This ‘flow-diverter’ might be positioned extra precisely and safely than present therapies, decreasing the danger of problems and having to make use of a number of gadgets.


The funding will allow the corporate to finish growth work and acquire first in-human information by an early feasibility scientific research, setting the scene for an additional fundraise for bigger FDA and CE Mark scientific trials.


The world mind aneurysm remedy market was valued at more than $2.184 billion  in 2019 and is predicted to develop to achieve greater than $6.222 billion by 2027.


Mike Karim, CEO of Oxford Endovascular, stated: “One of the most important challenges with regards to treating neurovascular illness is having gadgets with excessive efficacy while minimising hostile occasions.

“Studies show that often multiple attempts are made to place treatment devices, as they often have challenges of landing accurately, opening and maintaining position. This can lead to adverse events and multiple devices being used. Procedures typically cost over $50,000 to treat a brain aneurysm and a next generation flow diverter overcoming unmet needs, offers the chance for more effective, safer and cost-effective treatments as well as allowing many more patients to benefit.”

Martin Diggle, portfolio supervisor, life sciences at Vulpes Investment Management, stated: “We believe this platform has the potential to become a world leader in its field.”

Alun Williams, funding director at Parkwalk Advisors, stated: “This raise is testament to the extraordinary work and innovation of a great team of development engineers and inventors and will help the company through its next stages of research.”

Nick Dixon-Clegg, funding principal at Oxford Sciences Innovationstated: “Oxford Sciences Innovation has invested in Oxford Endovascular since seed stage, and we are pleased to continue to do so.”

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